Sunday 10 June 2012

Warfarin Diet

Warfarin Diet
Patient should be educated to maintain consistent diet to optimize warfarin therapy. Vitamin K high containing food (reduce INR) should be reduced to minimize inteference with warfarin therapy. Examples of vitamin K high content food include leafy green vegetables, certain vegetable oils such as canola or soybean. 
Besides, patient should let their doctor or pharmacist know any supplement or medications taken including herbal products. Products such as coenzyme Q10, cranberry products, dong quai, garlic, Ginkgo biloba, ginseng, and St. John's wort would have affected warfarin therapy.
Furthermore, some medications like NSAID (ibuprofen, acetaminophen) and Aspirin would have increase INR value leading to higher risk of bleeding. Warfarin dose would be adjusted if patient is concurrently taking these medications. 
Also, certain antibiotics including azole group of antifungals (Fluconazole, Itraconazole), Metronidazole, Bactrim, Amiodarone would have lead to a significant increase in INR and should be taken into consideration before starting warfarin therapy.

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