Related searches: Warfarin bone loss, warfarin bone fracture, warfarin bone health, warfarin bone deformity
Long-term use of warfarin is associated witth osteoporosis-related fractured. Study of 572 women in 1999 showed that risk of vertebral fracture and rib fracture was increased in patients taking warfarin for deep vein thrombosis. Also, retrospective study of 14564 Medicare recipients for more than 1 year demonstrated 60% increased risk of osteoporosis-related fracture in men, however, there was no association in women. The mechanism was thought due to the reduced intake of vitamin K responsible for bone health.
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